Great Lakes Clinical Trials Recruiting Adults Who Recently Tested Positive for COVID-19

BLAZE-1 Study is evaluating a potential COVID-19 antibody treatment following successful laboratory studies.

Chicago; August 19 , 2020 – Great Lakes Clinical Trials announced today it has begun recruiting and treating patients in a clinical research study to evaluate the safety and effectiveness of LY-CoV555 in patients with early mild to moderate COVID-19. Sponsored by Eli Lilly and Company (Lilly), the BLAZE-1 Study is looking for adults ages 18 or older who have recently tested positive for COVID-19 and are not hospitalized.

LY-CoV555 is an antibody therapy engineered from one of the first individuals in the U.S. to recover from COVID-19 and is specifically designed to attack SARS-CoV-2, the virus that causes COVID-19.Laboratory studies have shown that LY-CoV555 binds with high affinity to the SARS-CoV-2 virus and neutralizes its ability to infect cells and replicate.

“Clinical trials like BLAZE-1 are vital in testing potential treatments for COVID-19 which, if successful, represent medicines which can be used to protect those most at risk of severe illness, such as the elderly and immunocompromised,” said Steve Satek, President & Founder, Great Lakes Clinical Trials. “Great Lakes Clinical Trials has been on the front lines of the fight against COVID-19, and we are honored to participate in this important, landmark study with Lilly to potentially bring effective COVID-19 treatment to the public faster.”

To be eligible for the BLAZE-1 Study, participants must have tested positive for SARS-CoV-2 infection within three days prior to the study drug infusion, and have one or more mild or moderate COVID-19 symptoms, including, fever, cough, sore throat, headache, muscle pain, nausea, abdominal pain, diarrhea, or shortness of breath when active.

If a person is eligible and decides to participate, the research staff at Great Lakes Clinical Trials will perform specific tests and procedures to monitor the patient’s health and how their body reacts to the LY-CoV555 antibody treatment. These tests and procedures include physical exams, vital sign measurements, blood samples, and nasopharyngeal swabs to measure levels of virus.

The study drug is being compared to a placebo, and both the study drug and the placebo will be administered as a single-dose intravenous (IV) infusion. Participants will be randomly selected to receive the placebo or the study drug.

“Kicking off the BLAZE-1 Study with research sites around the country, including Great Lakes Clinical Trials, is a huge milestone for the global fight against COVID-19, and we’re excited to bring the industry one step closer to a potential treatment,” said Dr. Daniel Skovronsky, chief scientific officer, Eli Lilly and Company. “We look forward to working with eligible patients who are not only interested in receiving investigational treatments for COVID-19, but who also understand how their participation can impact the health and well-being of millions of people around the world.”

If someone has tested positive and exhibited symptoms for COVID-19, and are interested in participating in clinical research in their area, call 833.277.0197 or visit JoinCOVIDStudy.com to learn more.